英文药名：Desferal for injection（Deferoxamine Mesilate）
Desferal for injection
1. 与三价铁离子结合，以形成一个稳定的水溶性ferrioxamine B.其稳定性常数是1031，比EDTA（1025）（体外）更强。从理论上讲是甲磺酸去铁胺100毫克与3价铁离子结合8.5mg。
Desferal for injection 500mg（デスフェラール注射用500mg）
Brand name : Desferal for injection 500mg
Active ingredient: Deferoxamine mesilate
Dosage form: injection
Print on wrapping:
Effects of this medicine
This medicine is an iron chelator agent which binds and excretes excessively accumulated iron from the body into the urine or stool.
It is usually used to treat hemochromatosis (organ damage caused by excess iron).
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you are not able to urinate.
If you have renal/hepatic disorder or diabetes.
•If you are pregnant, breastfeeding or possibly pregnant.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, inject it intramuscularly 1 to 2 times a day. It may be administered intravenously at a slow speed
•Ask your doctor about your treatment span.
Precautions while taking this medicine
•This medicine may cause dizziness or visual/hearing impairment. Avoid driving a car or operating dangerous machinery if you have such symptoms.
•When this medicine binds with iron and is excreted in the urine, your urine may turn to a characteristic reddish color.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include hepatic dysfunction, malaise, visual disorder, skin disorders such as rash/erythema/urticaria, hearing disorder such as hearing loss and bone pain. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•urticaria, dyspnea, swelling around eyes/lips [shock, anaphylactoid symptoms]
•blurred vision, reduced visual acuity, unable to see color difference [eye disorder]
•hearing difficulty of voice or sound, tinnitus [hearing disorder]
•fever, diarrhea, abdominal pain [infection with Yersinia (bacterial infection)]
•fever, cough, sputum [infection with Mucormycosis (fungal infection)]
•decrease of urine volume, edema, thirst [acute renal failure, renal tubular disorders]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Novartis Pharma K.K.Injection
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.